Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 2/20 | 0.38 |
| ▸ | EEF2 | P13639 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667064 | 0.98 | CHKA (0.46) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Water SCHEMBL31529761 | 0.96 | CHKA (0.44) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Bromide SCHEMBL1041812 | 0.96 | CHKA (0.47) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Iodide SCHEMBL2195240 | 0.96 | CHKA (0.44) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| SCHEMBL2805388 | 0.91 | CHKA (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| SCHEMBL22265213 | 0.91 | CHKA (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| SCHEMBL22264518 | 0.91 | CHKA (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| SCHEMBL385273 | 0.91 | CHKA (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Bicarbonate SCHEMBL23698533 | 0.89 | MEN1 (0.46) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Phosphoric Acid SCHEMBL20531186 | 0.89 | MEN1 (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735622-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | Illumina, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | BASF SE (DE) | 2026-05-05 | — | — | US | claimed |
| EP-4453243-B1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA INC (US) | 2026-02-11 | — | — | EP | claimed |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BASF SE (DE) | 2025-12-30 | — | — | US | claimed |
| CN-119823109-A | An electrochromic material electrochromic composition and electrochromic device | 吉林大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119637938-A | Nitrogen-doped carbon intercalation MoS2Preparation method and application of @ MCNTs | 德州学院 | 2025-03-18 | — | — | CN | claimed |
| EP-4499871-A1 | METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA, INC. (US) | 2025-02-05 | — | — | EP | claimed |
| WO-2025003459-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | ILLUMINA, INC. (US) | 2025-01-02 | — | — | WO | claimed |
| US-20240401127-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA, INC. | 2024-12-05 | — | — | US | claimed |
| US-20240384327-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA, INC. | 2024-11-21 | — | — | US | claimed |
| CN-104143494-A | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RES CORP | 2014-11-12 | — | — | CN | claimed |
| CN-103391911-A | Method for hydrohalogenating alkynes and for producing chlorinated alkenes by hydrochlorination of alkynes | SOLVAY | 2013-11-13 | — | — | CN | claimed |
| CN-103269796-A | Catalytic system and its use for the manufacture of vinyl chloride by hydrochlorination of acetylene | SOLVAY | 2013-08-28 | — | — | CN | claimed |
| WO-2012113778-A1 | PROCESS FOR THE HYDROHALOGENATION OF AN ALKYNE AND FOR THE MANUFACTURE OF VINYL CHLORIDE BY HYDROCHLORINATION OF ACETYLENE | SOLVAY SA (BE) | 2012-08-30 | — | — | WO | claimed |
| US-20120207525-A1 | RESISTANCE HEATING COMPOSITION AND HEATING COMPOSITE, HEATING APPARATUS, AND FUSING APPARATUS, INCLUDING RESISTANCE HEATING COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-16 | — | — | US | claimed |
| US-8217100-B2 | Adhesive composition and optical member | CHEIL INDUSTRIES, INC. (KR) | 2012-07-10 | — | — | US | claimed |
| WO-2012084642-A1 | MANUFACTURE OF VINYL CHLORIDE BY HYDROCHLORINATION OF ACETYLENE IN THE PRESENCE OF A CATALYTIC SYSTEM CONSISTING OF AT LEAST ONE IONIC LIQUID | SOLVAY SA (BE) | 2012-06-28 | — | — | WO | claimed |
| WO-2012084644-A1 | CATALYTIC SYSTEM AND ITS USE FOR THE MANUFACTURE OF VINYL CHLORIDE BY HYDROCHLORINATION OF ACETYLENE | SOLVAY SA (BE) | 2012-06-28 | — | — | WO | claimed |
| US-8002969-B2 | Upgrading crude oil using electrochemically-generated hydrogen | SAUDI ARABIAN OIL COMPANY (SA) | 2011-08-23 | — | — | US | claimed |
| US-20090014123-A1 | Adhesive composition and optical member | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2009-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | UQCRB, SCO2, UTS2R | ALDH1A1 1224/4885KDM4E 2214/4885RAB9A 4723/4885 |
| US-20240401127-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | POLN, PNKP, POLB | ALDH1A1 4683/4885KDM4E 3701/4885RAB9A 4425/4885 |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BMP1, BMP4, PBRM1 | ALDH1A1 1995/4885KDM4E 180/4885RAB9A 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.