SCHEMBL20006680

SCHEMBL20006680

COc1cccc(F)c1C#Cc1cc(F)c(C(F)(F)Oc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.33
GRM4 Q14833 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20006664 0.91 AR (0.31) ARGRM4
SCHEMBL20004776 0.81 ERN1 (0.31)
SCHEMBL20006839 0.81 ERN1 (0.36) ARTDP1L3MBTL1
SCHEMBL20006718 0.81
SCHEMBL20006852 0.81 ALOX5AP (0.31)
SCHEMBL20005253 0.78 ERN1 (0.32)
SCHEMBL19999393 0.77 GPR55 (0.32)
SCHEMBL19999428 0.77 PTGS2 (0.32)
SCHEMBL19999604 0.77 ERN1 (0.33)
SCHEMBL20006840 0.77 ERN1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208249-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-02-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed