Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 12/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006805 | 0.85 | GHSR (0.56) | GHSRKMT2A | |
| SCHEMBL3637815 | 0.83 | GHSR (1.00) | GHSRKMT2AMEN1 | |
| SCHEMBL3631662 | 0.76 | GHSR (0.85) | GHSRKMT2AMEN1 | |
| SCHEMBL19995013 | 0.75 | GHSR (1.00) | GHSRMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL3638285 | 0.75 | GHSR (1.00) | GHSRKMT2AMEN1 | |
| SCHEMBL3637512 | 0.74 | GHSR (0.81) | GHSR | |
| SCHEMBL3631615 | 0.73 | GHSR (1.00) | GHSRKMT2ANPSR1MEN1TSHR | |
| SCHEMBL2473629 | 0.72 | KMT2A (0.51) | KMT2AALDH1A1MEN1GAATSHR | |
| SCHEMBL2470464 | 0.71 | CACNA1F (0.50) | GHSRKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL3636455 | 0.70 | GHSR (1.00) | GHSRKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055235-A1 | ISOXAZOLE-AMIDES FOR TREATING CARDIAC DISEASES | UNIVERSITY OF HELSINKI (FI) | 2018-03-29 | — | — | WO | disclosed |