Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 18/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631662 | 0.92 | GHSR (0.85) | GHSRPTGS2MEN1KMT2A | |
| SCHEMBL3638285 | 0.91 | GHSR (1.00) | GHSRPTGS2MEN1KMT2A | |
| SCHEMBL3637512 | 0.90 | GHSR (0.81) | GHSR | |
| SCHEMBL3631615 | 0.89 | GHSR (1.00) | GHSRPTGS2MEN1KMT2A | |
| SCHEMBL3637769 | 0.86 | GHSR (1.00) | GHSRPTGS2 | |
| SCHEMBL3637357 | 0.84 | GHSR (1.00) | GHSR | |
| SCHEMBL20006737 | 0.83 | GHSR (0.72) | GHSRMEN1KMT2A | |
| SCHEMBL3639749 | 0.83 | GHSR (0.72) | GHSRKMT2A | |
| SCHEMBL3634973 | 0.83 | GHSR (0.88) | GHSR | |
| SCHEMBL3636499 | 0.81 | GHSR (1.00) | GHSRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | claimed |
| US-20100093638-A1 | TREAMENT FOR CHEMICAL SUBSTANCE ADDICTION | ABUNON AB (SE) | 2010-04-15 | — | — | US | disclosed |
| EP-2155227-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | Dickson, Suzanne L (SE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009020419-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | DICKSON SUZANNE L (SE) | 2009-02-12 | — | — | WO | disclosed |
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | GPR119, GIPR, GLP1R | GHSR 5/4885PTGS2 2925/4885MEN1 3388/4885 |
| US-20100093638-A1 | TREAMENT FOR CHEMICAL SUBSTANCE ADDICTION | GHSR, GHRHR, TRHR | GHSR 1/4885PTGS2 2302/4885MEN1 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.