Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887914 | 0.80 | PDK2 (0.42) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL29386757 | 0.77 | PDK2 (0.44) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL29363404 | 0.77 | HTR2A (0.48) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL283246 | 0.77 | HTR2A (0.48) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL18383337 | 0.77 | PDK2 (0.44) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL24729587 | 0.74 | HTR2A (0.47) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL28942003 | 0.74 | HTR2A (0.47) | PDK2THRBTDP1MAPTS100A4 | |
| Benzene SCHEMBL28919541 | 0.74 | PGR (0.48) | PDK2THRBTDP1MAPTS100A4 | |
| Lithium SCHEMBL30363455 | 0.74 | HTR2A (0.47) | PDK2THRBTDP1MAPTS100A4 | |
| SCHEMBL26331383 | 0.74 | HTR2A (0.47) | PDK2THRBTDP1MAPTS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10276805-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-04-30 | — | — | US | disclosed |
| US-20180090691-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180090691-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | EML4, TYR, CPNE4 | PDK2 839/4885THRB 4195/4885TDP1 4132/4885 |
| US-10276805-B2 | Organic electroluminescent materials and devices | EML4, TYR, CPNE4 | PDK2 839/4885THRB 4195/4885TDP1 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.