Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006948 | 0.81 | DRD2 (0.54) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL23940685 | 0.78 | DRD2 (0.49) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL20179482 | 0.78 | DRD2 (0.49) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL11943726 | 0.75 | HTR1A (0.78) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL23940671 | 0.75 | HTR1A (0.78) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL14240237 | 0.75 | HTR1A (0.78) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL14503843 | 0.75 | HTR1A (0.78) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL24263143 | 0.75 | HTR1A (0.78) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL6856896 | 0.74 | HTR1A (0.52) | DRD2SLC6A4HTR1AHTR2ACHRM1 | |
| SCHEMBL14681243 | 0.74 | HTR1A (0.52) | DRD2SLC6A4HTR1AHTR2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2018-03-28 | — | — | EP | disclosed |