SCHEMBL20007323

SCHEMBL20007323

Cc1cc(-c2ccc(-c3ccccc3-c3cc(Cl)cc(-c4ccccc4-c4ccc(-c5cc(C)c(-c6cccc(-c7ccccc7)c6)cn5)cc4)c3)cc2)ncc1-c1cccc(-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.45
ENPP3 O14638 1/20 0.39
ADORA1 P30542 3/20 0.39
ADORA2A P29274 1/20 0.39
MAP4K4 O95819 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
IRAK4 Q9NWZ3 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ESR2 Q92731 1/20 0.35
DHFR P00374 1/20 0.35
PIM1 P11309 1/20 0.35
ALDH1A2 O94788 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19834632 0.95 LDHA (0.49) LDHAENPP3ADORA1ADORA2AMAP4K4
SCHEMBL18015350 0.89 LDHA (0.49) LDHAADORA1ADORA2AMAP4K4MEN1
SCHEMBL20007050 0.89 LDHA (0.42) LDHAENPP3MAP4K4MEN1KMT2A
SCHEMBL19933558 0.88 LDHA (0.50) LDHAADORA1ADORA2AMEN1KMT2A
SCHEMBL22563336 0.87 LDHA (0.45) LDHAENPP3ADORA1MEN1KMT2A
SCHEMBL19833339 0.86 LDHA (0.40) LDHAADORA1MEN1KMT2ANPC1
SCHEMBL19833441 0.85 LDHA (0.50) LDHAENPP3MAP4K4MEN1KMT2A
SCHEMBL20007192 0.85 ENPP3 (0.36) LDHAENPP3ADORA1ADORA2AMAP4K4
SCHEMBL21397943 0.84 LDHA (0.40) LDHAENPP3NPC1RAB9AIRAK4
SCHEMBL20696568 0.84 ABL1 (0.47) LDHAADORA1ADORA2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
EP-3515925-B1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 US disclosed
WO-2018054798-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 LDHA 2122/4885ENPP3 930/4885ADORA1 4753/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 LDHA 2122/4885ENPP3 930/4885ADORA1 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.