Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12539197 | 0.85 | KDM4E (0.44) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL17168945 | 0.77 | NOS2 (0.39) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL2075967 | 0.76 | NOS2 (0.47) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL16033555 | 0.76 | KDM4E (0.42) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL24973136 | 0.71 | CA2 (0.47) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL2495475 | 0.70 | KCNH2 (0.48) | CYP3A4NOS2 | |
| SCHEMBL19214807 | 0.69 | KDM4E (0.37) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL23015776 | 0.69 | KDM4E (0.44) | KDM4ELMNACYP3A4TSHRNOS3 | |
| SCHEMBL1685607 | 0.68 | KCNH2 (0.52) | KDM4ELMNACYP3A4 | |
| SCHEMBL11815923 | 0.67 | PTGS2 (0.42) | KDM4ELMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2843743-B1 | Membrane electrode units for high temperature fuel cells with improved stability | BASF SE (DE) | 2018-03-28 | — | — | EP | disclosed |