Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630522 | 0.84 | ADORA3 (0.56) | ADORA3TP53TSHR | |
| SCHEMBL12652598 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL17900855 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL1800313 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL1797094 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL12652308 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL17900857 | 0.79 | ADORA3 (0.59) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL18630414 | 0.78 | NNMT (0.40) | ADORA2AADORA3ADORA1 | |
| SCHEMBL12652499 | 0.77 | UBA6 (0.62) | ADORA2AADORA2BADORA3ADORA1TP53 | |
| SCHEMBL1796596 | 0.77 | UBA6 (0.62) | ADORA2AADORA2BADORA3ADORA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | MILLENNIUM PHARMACEUTICALS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | TYMP, TYMS, PPA1 | ADORA2A 1750/4885ADORA2B 2252/4885ADORA3 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.