Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 14/20 | 0.33 |
| ▸ | BRAF | P15056 | 13/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677290 | 0.63 | MEN1 (0.46) | — | |
| SCHEMBL20825883 | 0.61 | NAAA (0.46) | — | |
| SCHEMBL20008808 | 0.61 | RAF1 (0.32) | RAF1BRAF | |
| SCHEMBL22561899 | 0.59 | ADCY1 (0.37) | RAF1BRAFABL1 | |
| SCHEMBL25739849 | 0.57 | SMN1; SMN2 (0.62) | — | |
| SCHEMBL23677135 | 0.57 | KMT2A (0.34) | — | |
| SCHEMBL6923831 | 0.57 | DYRK1A (0.42) | — | |
| SCHEMBL11345038 | 0.56 | CDK1 (0.33) | — | |
| SCHEMBL11350048 | 0.56 | NPC1 (0.46) | — | |
| SCHEMBL23654524 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |