Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008419 | 0.75 | RAF1 (0.39) | BRAFRAF1 | |
| SCHEMBL20010011 | 0.71 | BRAF (0.48) | BRAFRAF1 | |
| SCHEMBL20008527 | 0.63 | RAF1 (0.36) | BRAFRAF1 | |
| SCHEMBL20008232 | 0.62 | RAF1 (0.34) | BRAFRAF1 | |
| SCHEMBL20009217 | 0.59 | RAF1 (0.39) | BRAFRAF1 | |
| SCHEMBL20518208 | 0.58 | NFE2L2 (0.45) | — | |
| SCHEMBL20518125 | 0.57 | TLK2 (0.42) | — | |
| SCHEMBL24716509 | 0.57 | LMNA (0.41) | — | |
| SCHEMBL16118412 | 0.57 | NPC1 (0.39) | — | |
| SCHEMBL18719675 | 0.56 | PRSS1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |