Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008420 | 0.62 | NPC1 (0.43) | HTTMEN1KMT2A | |
| SCHEMBL24080970 | 0.58 | NOS3 (0.42) | CNR2HTTKDM4EMEN1LMNA | |
| SCHEMBL6598757 | 0.55 | KMT2A (0.66) | KMT2A | |
| SCHEMBL7485228 | 0.53 | KMT2A (0.49) | CNR2MEN1LMNAKMT2A | |
| SCHEMBL16945095 | 0.52 | CNR2 (0.53) | CNR2HTTKDM4ELMNA | |
| SCHEMBL14344739 | 0.51 | CCR1 (0.47) | KDM4EMEN1LMNAKMT2A | |
| SCHEMBL16408483 | 0.51 | TDP1 (0.63) | CNR2 | |
| SCHEMBL16546002 | 0.51 | TDP1 (0.63) | CNR2 | |
| SCHEMBL13151876 | 0.51 | KMT2A (0.71) | HTTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL12108751 | 0.51 | KMT2A (0.66) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |