Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.43 |
| ▸ | RAB9A | P51151 | 14/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.43 |
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.43 |
| ▸ | RELA | Q04206 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008317 | 0.62 | CNR2 (0.33) | KMT2AMEN1HTT | |
| SCHEMBL20008137 | 0.55 | PIK3C3 (0.31) | — | |
| SCHEMBL20009507 | 0.55 | MAPT (0.33) | MAPTALDH1A1ALOX12 | |
| SCHEMBL20008786 | 0.53 | RAF1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL20209312 | 0.52 | HPGD (0.52) | SMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL20008890 | 0.52 | RAF1 (0.49) | — | |
| SCHEMBL20008475 | 0.52 | RAF1 (0.39) | — | |
| SCHEMBL26739776 | 0.51 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1KMT2APOLB | |
| SCHEMBL26739736 | 0.51 | ALDH1A1 (0.40) | NPC1ALDH1A1MAPK1TP53HTT | |
| SCHEMBL19382084 | 0.51 | KIT (0.44) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |