Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425326 | 0.82 | KMT2A (0.59) | KDM4EKMT2AHTTPOLBCRHR1 | |
| SCHEMBL16454958 | 0.71 | KMT2A (0.41) | KDM4EKMT2AHTT | |
| SCHEMBL20008535 | 0.70 | VRK1 (0.31) | — | |
| SCHEMBL1424847 | 0.68 | KDM4E (0.42) | KDM4EKMT2ACRHR1 | |
| SCHEMBL1603021 | 0.67 | KMT2A (0.67) | KDM4EKMT2AHTTPOLBCRHR1 | |
| SCHEMBL9977693 | 0.66 | KMT2A (0.57) | KDM4EKMT2A | |
| SCHEMBL24899985 | 0.65 | KDM4E (0.54) | KDM4EKMT2AHTTPOLBCRHR1 | |
| SCHEMBL12484355 | 0.65 | KMT2A (0.42) | KDM4EKMT2AHTTCRHR1 | |
| SCHEMBL31511674 | 0.65 | SMN1; SMN2 (0.49) | KDM4EKMT2ACRHR1 | |
| SCHEMBL5844220 | 0.65 | KDM4E (0.50) | KDM4EKMT2AHTTCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |