Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VRK1 | Q99986 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008434 | 0.85 | CRHR1 (0.34) | — | |
| SCHEMBL20008358 | 0.81 | VRK1 (0.31) | VRK1 | |
| SCHEMBL20010275 | 0.74 | — | — | |
| SCHEMBL20008337 | 0.70 | KDM4E (0.43) | — | |
| SCHEMBL20008162 | 0.63 | CRHR1 (0.35) | — | |
| SCHEMBL20008488 | 0.62 | CYP19A1 (0.38) | — | |
| SCHEMBL1424847 | 0.59 | KDM4E (0.42) | — | |
| SCHEMBL13741410 | 0.59 | GBA1 (0.42) | — | |
| SCHEMBL10105111 | 0.57 | PSMB5 (0.49) | — | |
| SCHEMBL12484355 | 0.56 | KMT2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |