Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ADA | P00813 | 4/20 | 0.31 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008208 | 0.86 | CA1 (0.35) | PDE2APDE4DPOLBCDK1 | |
| SCHEMBL20008037 | 0.84 | ATG7 (0.40) | ATG7CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20008103 | 0.83 | ATG7 (0.34) | TSHRATG7POLBCCNB2CDK1 | |
| SCHEMBL20008410 | 0.82 | ATG7 (0.36) | CYP3A4CYP1A2SMN1; SMN2LARS1ATG7 | |
| SCHEMBL20007970 | 0.81 | DNPH1 (0.38) | CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL23080276 | 0.80 | ATG7 (0.34) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL20008059 | 0.78 | RET (0.33) | ATG7CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL23080286 | 0.78 | ADORA2A (0.36) | ADORA2AADORA2BADORA1CCNB2CDK1 | |
| SCHEMBL23080263 | 0.78 | ATG7 (0.32) | CYP3A4CYP1A2SMN1; SMN2ATG7BLM | |
| SCHEMBL20008098 | 0.77 | CDK1 (0.41) | ADORA2AADORA2BADORA1KDM4ECCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | MILLENNIUM PHARMACEUTICALS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | TYMP, TYMS, PPA1 | ADORA2A 1750/4885ADORA2B 2252/4885ADORA1 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.