Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009697 | 0.80 | — | — | |
| SCHEMBL5592985 | 0.64 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL27977991 | 0.64 | KMT2A (0.39) | — | |
| SCHEMBL2328573 | 0.61 | KDM4E (0.53) | — | |
| SCHEMBL25198432 | 0.61 | NOS2 (0.37) | CRHR1 | |
| SCHEMBL24364823 | 0.61 | NNMT (0.43) | — | |
| SCHEMBL2324851 | 0.61 | KMT2A (0.55) | — | |
| SCHEMBL22165795 | 0.60 | NOS3 (0.48) | — | |
| SCHEMBL2333526 | 0.59 | KDM4E (0.38) | — | |
| SCHEMBL15242259 | 0.59 | NOS3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |