Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008179 | 0.88 | MAPT (0.31) | MAPT | |
| SCHEMBL20008487 | 0.80 | NPC1 (0.36) | MAPT | |
| SCHEMBL20008388 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL20009447 | 0.78 | MAPT (0.33) | MAPT | |
| SCHEMBL20009507 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL20008301 | 0.76 | — | — | |
| SCHEMBL20008321 | 0.76 | OPRK1 (0.32) | MAPT | |
| SCHEMBL20008164 | 0.76 | MAPT (0.32) | MAPT | |
| SCHEMBL20008391 | 0.70 | — | — | |
| SCHEMBL20008394 | 0.68 | RAB9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |