Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 9/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008661 | 0.91 | PRSS1 (0.47) | PRSS1TMPRSS15F2MAPTKMT2A | |
| SCHEMBL20008669 | 0.89 | NR1H4 (0.45) | PRSS1TMPRSS15F2PLGPLAU | |
| SCHEMBL20008692 | 0.89 | F10 (0.39) | PRSS1TMPRSS15F2PLGKLK1 | |
| SCHEMBL20008677 | 0.82 | KMT2A (0.39) | PRSS1TMPRSS15F2MAPTKMT2A | |
| SCHEMBL11309396 | 0.80 | PRSS1 (0.52) | PRSS1TMPRSS15F2MAPTKMT2A | |
| SCHEMBL20008680 | 0.80 | F2 (0.51) | PRSS1TMPRSS15F2KLK1SLC22A2 | |
| SCHEMBL20008674 | 0.78 | PRSS1 (0.42) | PRSS1TMPRSS15F2KLK1SLC22A2 | |
| SCHEMBL20008675 | 0.78 | PRSS1 (0.36) | PRSS1TMPRSS15F2MAPTKMT2A | |
| SCHEMBL20008683 | 0.77 | PRSS1 (0.45) | PRSS1TMPRSS15F2GAAPLG | |
| SCHEMBL11305428 | 0.76 | PRSS1 (0.56) | PRSS1TMPRSS15F2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | PRSS1 952/4885TMPRSS15 87/4885F2 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.