SCHEMBL20009218

SCHEMBL20009218

CCCCCCCCCCCCCCCCCCCCCC(=O)OC(CS(=O)(=O)O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 1/20 0.45
PRKCA P17252 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCD Q05655 1/20 0.42
FAAH O00519 7/20 0.41
CES1 P23141 5/20 0.41
CES2 O00748 2/20 0.41
DGKA P23743 1/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18775675 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775662 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775743 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775730 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775656 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL20009227 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775692 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775694 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL18775661 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL20009222 1.00 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086948-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING A BIO-ELECTRODE, AND SALT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086948-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING A BIO-ELECTRODE, AND SALT SLC9A1, FN1, EPCAM LMNA 2893/4885MAPT 3241/4885MAPK1 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.