SCHEMBL20009365

SCHEMBL20009365

O=C(O[C@@H]1C(O)[C@H](O)OC(CO)[C@H]1O)c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 7/20 0.56
LGALS9 O00182 6/20 0.56
LGALS1 P09382 6/20 0.56
LGALS7; LGALS7B P47929 5/20 0.56
LGALS8 O00214 5/20 0.56
LGALS4 P56470 1/20 0.44
SLC28A3 Q9HAS3 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
BCHE P06276 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SLC5A1 P13866 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14665819 1.00 LGALS3 (0.56) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL19754919 1.00 LGALS3 (0.56) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8360632 0.83 LGALS3 (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL12482435 0.82 LGALS3 (0.76) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL4652290 0.81 SLC28A3 (0.55) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL20009375 0.79 LGALS9 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL20307167 0.78 SLC5A1 (0.44) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL1075010 0.77 SLC28A3 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL25225023 0.77 LGALS9 (0.51) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL28036435 0.77 LGALS9 (0.51) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018053706-A1 COMPOSITION COMPRISING PAEONIFLORIN OR ALBIFLORIN ANALOGUE, METHOD OF PREPARATION THEREOF L'OREAL (FR) 2018-03-29 WO disclosed