SCHEMBL20009375

SCHEMBL20009375

O=C(O[C@H]1C(O)C(CO)O[C@@H](O)C1O)c1ccccc1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 3/20 0.49
LGALS1 P09382 3/20 0.49
LGALS3 P17931 3/20 0.49
LGALS7; LGALS7B P47929 3/20 0.49
LGALS8 O00214 3/20 0.49
HTT P42858 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SGMS2 Q8NHU3 3/20 0.43
LMNA P02545 1/20 0.42
ALDH1A1 P00352 1/20 0.42
NPC1 O15118 1/20 0.42
PARP1 P09874 1/20 0.41
SLC6A2 P23975 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
GAA P10253 1/20 0.41
PPIA P62937 1/20 0.41
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009378 0.84 HTT (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL28497434 0.81 HTT (0.47) LGALS8HTTMEN1KMT2ASMN1; SMN2
SCHEMBL20009365 0.79 LGALS3 (0.56) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL19754919 0.79 LGALS3 (0.56) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL14665819 0.79 LGALS3 (0.56) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL12482435 0.78 LGALS3 (0.76) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL9800965 0.77 SLC6A2 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL22034477 0.77 SLC6A2 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL9791499 0.77 SLC6A2 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8
SCHEMBL8328411 0.77 SLC6A2 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018053706-A1 COMPOSITION COMPRISING PAEONIFLORIN OR ALBIFLORIN ANALOGUE, METHOD OF PREPARATION THEREOF L'OREAL (FR) 2018-03-29 WO disclosed