Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009375 | 0.84 | LGALS9 (0.49) | HTTTRPM8LGALS8SGMS2MEN1 | |
| SCHEMBL16986935 | 0.78 | LGALS9 (0.37) | LGALS8KMT2ALGALS9 | |
| SCHEMBL16986936 | 0.78 | LGALS9 (0.37) | LGALS8KMT2ALGALS9 | |
| SCHEMBL13775034 | 0.74 | SSTR5 (0.37) | LGALS8LGALS3 | |
| SCHEMBL22721951 | 0.72 | SSTR1 (0.41) | — | |
| SCHEMBL23488116 | 0.72 | ADRB2 (0.41) | LGALS8LGALS3 | |
| SCHEMBL22490885 | 0.72 | ADRB2 (0.41) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1926182 | 0.71 | KDM4E (0.48) | HTTTRPM8SGMS2PTGER1MEN1 | |
| SCHEMBL1926179 | 0.71 | KDM4E (0.48) | HTTTRPM8SGMS2PTGER1MEN1 | |
| SCHEMBL12582928 | 0.71 | TSHR (0.40) | LGALS8MEN1KMT2ASMN1; SMN2LGALS9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053706-A1 | COMPOSITION COMPRISING PAEONIFLORIN OR ALBIFLORIN ANALOGUE, METHOD OF PREPARATION THEREOF | L'OREAL (FR) | 2018-03-29 | — | — | WO | disclosed |