Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008286 | 0.66 | — | — | |
| SCHEMBL20009832 | 0.65 | — | — | |
| SCHEMBL19068913 | 0.61 | RAF1 (0.53) | RAF1BRAF | |
| SCHEMBL20009394 | 0.55 | BRAF (0.70) | RAF1BRAF | |
| SCHEMBL20009452 | 0.55 | RAF1 (0.44) | RAF1BRAF | |
| SCHEMBL20009609 | 0.53 | BTK (0.32) | BRAF | |
| SCHEMBL20008272 | 0.52 | TP53 (0.40) | — | |
| SCHEMBL20008223 | 0.50 | TP53 (0.39) | — | |
| SCHEMBL23197862 | 0.49 | KDM4E (0.34) | — | |
| SCHEMBL20008308 | 0.49 | NPC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |