Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 14/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009442 | 0.74 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL20009426 | 0.58 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL12484553 | 0.55 | KCNH3 (0.46) | — | |
| SCHEMBL13237061 | 0.54 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL6919531 | 0.53 | — | — | |
| SCHEMBL30063519 | 0.52 | NOS1 (0.69) | NOS1 | |
| Hydrochloric Acid SCHEMBL1995837 | 0.52 | — | — | |
| SCHEMBL26165713 | 0.51 | KDR (0.45) | RAF1BRAF | |
| SCHEMBL12484734 | 0.51 | KCNH3 (0.48) | — | |
| SCHEMBL29536522 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |