Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | FPR2 | P25090 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FPR3 | P25089 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727476 | 0.85 | FPR2 (0.77) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL20013751 | 0.85 | ALDH1A1 (0.73) | PKMFPR2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL12040473 | 0.84 | FPR2 (0.76) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL726965 | 0.82 | FPR2 (0.58) | PKMFPR2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL728702 | 0.79 | ALDH1A1 (0.74) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL728698 | 0.78 | FPR2 (0.74) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL20009933 | 0.78 | ALDH1A1 (0.72) | PKMALDH1A1NPSR1POLBTP53 | |
| SCHEMBL726966 | 0.78 | FPR2 (0.78) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL728706 | 0.77 | FPR2 (0.72) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 | |
| SCHEMBL726819 | 0.76 | FPR2 (1.00) | PKMFPR2ALDH1A1SMN1; SMN2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086696-A1 | RUNX2 Transcription Factor Inhibitors and Uses Thereof | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086696-A1 | RUNX2 Transcription Factor Inhibitors and Uses Thereof | CBFB, RUNX1, NCOA3 | PKM 4632/4885FPR2 2578/4885ALDH1A1 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.