SCHEMBL20010568

SCHEMBL20010568

CCOc1ccc(-c2ccc(OC(F)(F)F)c(F)c2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FGFR2 P21802 2/20 0.41
FGFR1 P11362 1/20 0.41
ALOX5AP P20292 2/20 0.40
FEN1 P39748 2/20 0.40
FAAH O00519 1/20 0.39
HCRTR1 O43613 4/20 0.39
HCRTR2 O43614 4/20 0.39
NAAA Q02083 2/20 0.39
CTSK P43235 1/20 0.39
PIM1 P11309 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
PDE2A O00408 1/20 0.39
EPHX2 P34913 1/20 0.38
S1PR1 P21453 1/20 0.37
KDM1A O60341 2/20 0.37
PTPRC P08575 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16855917 0.88 FGFR2 (0.46) FGFR2FGFR1FAAHNAAAKDM1A
SCHEMBL17490326 0.87 HCRTR1 (0.42) FGFR2FGFR1HCRTR1HCRTR2PDE2A
SCHEMBL18134240 0.85 PTGS2 (0.43) ALOX5APFEN1NAAACTSKPDE2A
SCHEMBL16855916 0.84 PTGS2 (0.50) FGFR2FGFR1
SCHEMBL18134264 0.83 FGFR2 (0.45) FGFR2FGFR1FAAHNAAAKDM1A
SCHEMBL20010648 0.83 KIF11 (0.43) FGFR2FGFR1
SCHEMBL9060677 0.82 L3MBTL1 (0.43) FGFR2FGFR1HCRTR1HCRTR2S1PR1
SCHEMBL18134239 0.82 PDE2A (0.40) ALOX5APFEN1FAAHNAAACTSK
SCHEMBL16855899 0.81 L3MBTL1 (0.43) FGFR2FGFR1FAAHNAAAKDM1A
SCHEMBL16855895 0.81 L3MBTL1 (0.43) FGFR2FGFR1FAAHNAAAKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10883047-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-01-05 US disclosed
US-20180086980-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-03-29 US disclosed
US-20180086980-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-03-29 US disclosed