Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10251915 | 1.00 | OPRL1 (0.35) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL10251299 | 0.95 | OPRL1 (0.34) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL20010738 | 0.94 | KDM4E (0.39) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL10251377 | 0.94 | KDM4E (0.39) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL18080681 | 0.93 | MEN1 (0.40) | OPRL1TAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL10250910 | 0.89 | GAA (0.41) | TAS1R3TAS1R1MMP9SMN1; SMN2 | |
| SCHEMBL20010736 | 0.87 | TAS1R3 (0.38) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL10251318 | 0.87 | TAS1R3 (0.38) | OPRL1TLR8TAS1R3TAS1R1MMP9 | |
| SCHEMBL10251264 | 0.86 | SMN1; SMN2 (0.38) | OPRL1SMN1; SMN2 | |
| SCHEMBL10251440 | 0.86 | SMN1; SMN2 (0.38) | OPRL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086751-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086751-A1 | SWEETENER COMPOSITION | TAS2R50, TAS1R2, TAS2R10 | OPRL1 4501/4885TLR8 950/4885TAS1R3 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.