Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20011254 | 0.88 | ALDH1A1 (0.64) | ALDH1A1GAASMN1; SMN2PKMMAPT | |
| SCHEMBL22607227 | 0.74 | ALDH1A1 (0.76) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL7990085 | 0.73 | RAB9A (0.77) | ALDH1A1GAASMN1; SMN2MAPTTP53 | |
| SCHEMBL17068762 | 0.71 | HTT (0.68) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL16157180 | 0.70 | SMN1; SMN2 (0.76) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL9058883 | 0.70 | HTT (0.79) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL26051623 | 0.68 | HPGD (0.67) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL16157161 | 0.67 | HTT (0.70) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL3612855 | 0.67 | RAB9A (0.97) | ALDH1A1GAASMN1; SMN2PKMHTT | |
| SCHEMBL16944482 | 0.66 | RECQL (1.00) | ALDH1A1GAASMN1; SMN2PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055627-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2018-03-29 | — | — | WO | disclosed |