Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 20/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20011328 | 0.84 | PARG (0.33) | PARG | |
| SCHEMBL18256094 | 0.76 | TRPA1 (0.44) | PARG | |
| SCHEMBL18255886 | 0.70 | TNF (0.52) | PARG | |
| SCHEMBL20011251 | 0.69 | TRPA1 (0.36) | PARG | |
| SCHEMBL19987804 | 0.69 | PARG (0.36) | PARG | |
| SCHEMBL18256055 | 0.68 | FEN1 (0.46) | PARG | |
| SCHEMBL18255869 | 0.68 | PARG (0.39) | PARG | |
| SCHEMBL18255872 | 0.67 | PARG (0.40) | PARG | |
| SCHEMBL18255772 | 0.67 | ADORA2B (0.57) | — | |
| SCHEMBL18255885 | 0.67 | TNF (0.53) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |