Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.64 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.64 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL394643 | 0.98 | CARM1 (0.62) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL11109064 | 0.98 | CARM1 (0.62) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL3642056 | 0.89 | CARM1 (0.53) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| SCHEMBL2058653 | 0.88 | SIGMAR1 (0.65) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| SCHEMBL7055109 | 0.86 | CARM1 (0.75) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL1593475 | 0.86 | SIGMAR1 (0.62) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| SCHEMBL11203747 | 0.86 | SIGMAR1 (0.68) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL11872505 | 0.84 | SIGMAR1 (0.71) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL11308286 | 0.84 | CARM1 (0.51) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| SCHEMBL1088446 | 0.82 | SIGMAR1 (0.74) | CARM1PRMT6PRMT8SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426987-B1 | RAPIDLY IMMOBILIZING PAPER COATING COMPOSITIONS | National Starch and Chemical Investment Holding Corporation (US) | 1993-07-14 | — | — | EP | claimed |
| US-5093159-A | Cationic Starch, Pigment, Base | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-03-03 | — | — | US | claimed |
| EP-0426987-A1 | Rapidly immobilizing paper coating compositions | National Starch and Chemical Investment Holding Corporation (US) | 1991-05-15 | — | — | EP | claimed |
| CN-117209418-A | Preparation and purification method of high-purity nicardipine hydrochloride | 华仁医学研究(安徽)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-109415345-B | Pyridazinone-based broad-spectrum anti-influenza inhibitors | 豪夫迈·罗氏有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-20210053971-A1 | CRYSTAL FORM OF MONOMETHANESULFONATE OF DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL COMPOUND AND PREPARATION METHOD THEREFOR | NANJING CAREPHAR SHENGHUI PHARMACEUTICAL CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| EP-3498708-B1 | DEUTERATED 3-(4,5-SUBSTITUTED PYRIMIDINAMINE) PHENYL DERIVATIVES AND APPLICATIONS THEREOF | NANJING CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |
| EP-3747887-A1 | CRYSTAL FORM OF MONOMETHANESULFONATE OF DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL COMPOUND, AND PREPARATION METHOD THEREFOR | Nanjing Chuangte Pharmaceutical Technology Co., Ltd (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-10654851-B2 | Deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof | Nanjing Chuangte Pharmaceutical Technology Co., Ltd. (CN) | 2020-05-19 | — | — | US | disclosed |
| WO-2019174623-A1 | CRYSTAL FORM OF MONOMETHANESULFONATE OF DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL COMPOUND, AND PREPARATION METHOD THEREFOR | 南京创特医药科技有限公司 | 2019-09-19 | — | — | WO | disclosed |
| US-20190225610-A1 | DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL DERIVATIVES AND USE THEREOF | Nanjing Chuangte Pharmaceutical Technology Co., Ltd (CN) | 2019-07-25 | — | — | US | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4150032-A | ANALGESIC, ANTITUSSIVE | BRISTOL-MYERS COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | disclosed |
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-4021557-A | BRONCHOSPASMOLYTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4016167-A | ANALGESICS, NARCOTIC ANTAGONISTS | BRISTOL-MYERS COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3956336-A | NARCOTIC ANTAGONIST, ANALGESICS | BRISTOL-MYERS COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053971-A1 | CRYSTAL FORM OF MONOMETHANESULFONATE OF DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL COMPOUND AND PREPARATION METHOD THEREFOR | EGFR, WEE1, HDGF | CARM1 4523/4885PRMT6 1710/4885PRMT8 2619/4885 |
| US-20190225610-A1 | DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL DERIVATIVES AND USE THEREOF | EGFR, ERBB2, ERBB4 | CARM1 3798/4885PRMT6 740/4885PRMT8 1410/4885 |
| US-10654851-B2 | Deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof | EGFR, ERBB2, ERBB4 | CARM1 3798/4885PRMT6 740/4885PRMT8 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.