Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ACP3 | P15309 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012472 | 0.82 | SIGMAR1 (0.47) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL10695877 | 0.78 | SIGMAR1 (0.55) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL10134832 | 0.78 | SIGMAR1 (0.55) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL7922002 | 0.78 | SIGMAR1 (0.55) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL143708 | 0.75 | SIGMAR1 (0.65) | SIGMAR1POLBMEN1KMT2ATAAR1 | |
| SCHEMBL22899588 | 0.75 | SIGMAR1 (0.65) | SIGMAR1POLBMEN1KMT2ATAAR1 | |
| Bromide SCHEMBL1331742 | 0.73 | SIGMAR1 (0.63) | SIGMAR1POLBMEN1KMT2ATAAR1 | |
| Ammonia Solution, Strong SCHEMBL15917374 | 0.73 | SIGMAR1 (0.63) | SIGMAR1POLBMEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL1331235 | 0.73 | SIGMAR1 (0.63) | SIGMAR1POLBMEN1KMT2ATDP1 | |
| SCHEMBL6601694 | 0.72 | SIGMAR1 (0.49) | SIGMAR1ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675787-B1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | ENDO PHARMACEUTICALS INC (US) | 2018-03-28 | — | — | EP | disclosed |