⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263123 | 1.00 | NOS3 (0.52) | — | |
| SCHEMBL29606666 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2104048 | 0.97 | — | — | |
| SCHEMBL1256200 | 0.84 | NOS3 (0.44) | — | |
| SCHEMBL3499564 | 0.75 | DYRK1A (0.59) | — | |
| SCHEMBL29432634 | 0.75 | DYRK1A (0.59) | — | |
| SCHEMBL2642278 | 0.74 | — | — | |
| SCHEMBL21394569 | 0.72 | NOS3 (0.50) | — | |
| SCHEMBL4402187 | 0.72 | DYRK1A (0.63) | — | |
| SCHEMBL43935 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2406 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241427-A | Method for comprehensively and efficiently synthesizing anticancer drug regorafenib | 董帅圻 | 2025-01-03 | — | — | CN | claimed |
| CN-118561748-B | Method for preparing 2-amino-4-chloro-5-nitropyridine | 山东仁一生物科技有限责任公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118561748-A | Method for preparing 2-amino-4-chloro-5-nitropyridine | 山东仁一生物科技有限责任公司 | 2024-08-30 | — | — | CN | claimed |
| CN-117654560-B | Method for continuously preparing nitro compound by oxidizing amino | 安徽泽升科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117654560-A | Method for continuously preparing nitro compound by oxidizing amino | 安徽泽升科技股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-113402450-B | Purification method of 2-bromo-4-chloropyridine | 上海睿腾医药科技有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-112430322-B | Covalent organic framework material based on imidazo [1,2-a ] pyridine connection and synthesis method thereof | 兰州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-112409354-B | Synthesis process of 7-fluoroimidazo [1,2-A ] pyridine and intermediate thereof | 苏利制药科技江阴有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-112867716-A | Solid forms of FGFR inhibitors and methods for their preparation | 因赛特公司 | 2021-05-28 | — | — | CN | claimed |
| EP-3788047-A2 | SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME | Incyte Corporation (US) | 2021-03-10 | — | — | EP | claimed |
| EP-2244706-B1 | GLUCOKINASE ACTIVATORS | MERCK PATENT GMBH (DE) | 2016-04-06 | — | — | EP | claimed |
| WO-2015157360-A1 | PROCESSES TO MAKE PROTEIN KINASE INHIBITORS | ABBVIE INC. (US) | 2015-10-15 | — | — | WO | claimed |
| CN-103420903-A | Method for synthesizing 5-Bromo-2, 4-dichloropyridine | TIANJIN ANJIN SCIENCE AND TECHNOLOGY DEV CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-102321312-B | Environment-friendly calcium zinc stabilizer for PVC pipe and preparation method thereof | GUANGDONG RUOTIAN NEW MATERIAL TECHNOLOGY CO LTD | 2013-08-07 | — | — | CN | claimed |
| CN-102321312-A | Environment-friendly calcium zinc stabilizer for PVC pipe and preparation method thereof | GUANGDONG RUOTIAN NEW MATERIAL TECHNOLOGY CO LTD | 2012-01-18 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| CN-101959515-A | Glucokinase activators | MERCK PATENT GMBH | 2011-01-26 | — | — | CN | claimed |
| EP-2244706-A1 | GLUCOKINASE ACTIVATORS | Merck Patent GmbH (DE) | 2010-11-03 | — | — | EP | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| WO-2009106203-A1 | GLUCOKINASE ACTIVATORS | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | WO | claimed |