Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21384143 | 0.98 | NOS1 (0.49) | NOS3NOS1NOS2MPOBACE1 | |
| SCHEMBL18586524 | 0.82 | MPO (0.55) | NOS3NOS1MPOPNMTTAAR1 | |
| SCHEMBL1600990 | 0.82 | NOS3 (0.57) | NOS3NOS1NOS2MPOTAAR1 | |
| SCHEMBL3300276 | 0.79 | PNMT (0.65) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL1501368 | 0.78 | ALDH1A1 (0.55) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL21384277 | 0.78 | PNMT (0.47) | NOS3NOS1MPOBACE1PNMT | |
| SCHEMBL29442853 | 0.78 | PNMT (0.47) | NOS3NOS1MPOBACE1PNMT | |
| SCHEMBL21384198 | 0.77 | TP53 (0.55) | MPOBACE1PNMTTAAR1CYP3A4 | |
| SCHEMBL29442835 | 0.77 | TP53 (0.55) | MPOBACE1PNMTTAAR1CYP3A4 | |
| SCHEMBL21394729 | 0.76 | TAAR1 (0.42) | MPOBACE1PNMTTAAR1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |