SCHEMBL200141

SCHEMBL200141

CC(=O)Cc1cccc(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.56
ENPP2 Q13822 1/20 0.52
CHRM2 P08172 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
DRD2 P14416 2/20 0.48
DRD1 P21728 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CYP3A4 P08684 3/20 0.47
CYP1A2 P05177 2/20 0.47
PKM P14618 1/20 0.47
ALOX15 P16050 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415008 0.89 GRIA2 (0.58) CTBP2CYP3A4CYP1A2
SCHEMBL6509671 0.87 ALDH1A1 (0.46) CTBP2CYP1A2ALDH1A1
SCHEMBL30427127 0.83 CTBP2 (0.59) CTBP2ENPP2CHRM2CHRM1CHRM3
SCHEMBL22981807 0.83 CTBP2 (0.59) CTBP2ENPP2CHRM2CHRM1CHRM3
SCHEMBL7767320 0.83 ENPP2 (0.56) CTBP2ENPP2CHRM2CHRM1CHRM3
3-Hydroxyphenylacetate SCHEMBL21114397 0.81 CTBP2 (0.62) CTBP2ENPP2DRD2DRD1TAAR1
3-Hydroxyphenylacetate SCHEMBL30024342 0.81 CTBP2 (0.62) CTBP2ENPP2DRD2DRD1TAAR1
SCHEMBL21997278 0.81 GRIA2 (0.50) ENPP2ALDH1A1
3-Hydroxyphenylacetate SCHEMBL337470 0.81 CTBP2 (0.62) CTBP2ENPP2DRD2DRD1TAAR1
3-Hydroxyphenylacetate SCHEMBL30690861 0.81 CTBP2 (0.62) CTBP2ENPP2DRD2DRD1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118666696-A Synthesis and refining method of meta-hydroxylamine bitartrate 玉门千华制药有限公司 2024-09-20 CN claimed
EP-2619174-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE Ind-Swift Laboratories Limited (IN) 2013-07-31 EP claimed
WO-2012038974-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2012-03-29 WO claimed
CN-1882307-A Method for dyeing fibres containing keratine HENKEL KGAA (DE) 2006-12-20 CN claimed
WO-1993010071-A1 PROCESS FOR THE PRODUCTION OF CARBONYLS CATALYTICA, INC. (US) 1993-05-27 WO claimed
CN-118685463-B Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies 杭州微远生物科技有限公司 2025-04-25 CN disclosed
CN-118666695-B Synthesis method of meta-hydroxylamine bitartrate 玉门千华制药有限公司 2024-12-17 CN disclosed
CN-118685463-A Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies 杭州微远生物科技有限公司 2024-09-24 CN disclosed
CN-118666695-A Synthesis method of meta-hydroxylamine bitartrate 玉门千华制药有限公司 2024-09-20 CN disclosed
CN-118666696-A Synthesis and refining method of meta-hydroxylamine bitartrate 玉门千华制药有限公司 2024-09-20 CN disclosed
CN-117800802-A Butanedione mediated benzyl C-H compound, halogeno compound, alkene, alkyne or alcohol oxidation method 遵义医科大学 2024-04-02 CN disclosed
CN-111349076-B Crystal form of L-lysine salt of benzopiperidine derivative and preparation method thereof 江苏恒瑞医药股份有限公司 2022-07-26 CN disclosed
US-5166210-A QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1992-11-24 US disclosed
US-5135863-A Immunoassay; drug abuse SYNTEX (U.S.A.) INC. (US) 1992-08-04 US disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-5028615-A Treatment of hypersensitivity RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-07-02 US disclosed
EP-0375422-A2 Composition and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine BEHRINGWERKE Aktiengesellschaft (DE) 1990-06-27 EP disclosed
US-4920133-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
WO-1989004305-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 WO disclosed