SCHEMBL21997278

SCHEMBL21997278

CC(=O)Cc1cccc(-c2cccc(CC(C)=O)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 2/20 0.50
BCL2 P10415 1/20 0.49
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
SHMT1 P34896 1/20 0.44
SHMT2 P34897 1/20 0.44
PTGS2 P35354 2/20 0.44
AOC3 Q16853 2/20 0.44
FAAH O00519 1/20 0.43
NAAA Q02083 1/20 0.43
AGXT P21549 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ENPP2 Q13822 1/20 0.42
CFD P00746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15214656 0.94 BCL2 (0.53) GRIA2BCL2GRIN2DGRIN3BGRIN1
SCHEMBL2302646 0.92 BCL2 (0.56) GRIA2BCL2GRIN2DGRIN3BGRIN1
SCHEMBL8415008 0.91 GRIA2 (0.58) GRIA2BCL2
SCHEMBL8263689 0.91 CTBP2 (0.49) GRIA2BCL2SHMT1SHMT2
SCHEMBL8413101 0.89 MMP3 (0.54) GRIA2BCL2SHMT1SHMT2PTGS2
SCHEMBL2302284 0.89 AOC3 (0.51) GRIA2SHMT1SHMT2AOC3
SCHEMBL5067092 0.89 GRIA2 (0.44) GRIA2BCL2GRIN2DGRIN3BGRIN1
SCHEMBL6509671 0.89 ALDH1A1 (0.46) GRIA2ALDH1A1
SCHEMBL2304146 0.88 AGXT (0.57) GRIA2BCL2SHMT1SHMT2PTGS2
SCHEMBL2303566 0.88 BCL2 (0.47) GRIA2BCL2GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10934389-B2 Methanesulfonic acid mediated solvent free synthesis of conjugated porous polymer networks THE TEXAS A&M UNIVERSITY SYSTEM (US) 2021-03-02 US disclosed
US-20200148812-A1 Methanesulfonic Acid Mediated Solvent Free Synthesis of Conjugated Porous Polymer Networks THE TEXAS A&M UNIVERSITY SYSTEM 2020-05-14 US disclosed