Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 4/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878862 | 0.93 | SMYD3 (0.41) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17879069 | 0.92 | SMYD3 (0.40) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17878864 | 0.91 | LDHA (0.43) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17740891 | 0.91 | SMYD3 (0.42) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17878892 | 0.90 | SMYD3 (0.41) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17730317 | 0.90 | SMYD3 (0.44) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17878876 | 0.90 | SMYD3 (0.42) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17878882 | 0.89 | SMYD3 (0.43) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17878890 | 0.88 | SMYD3 (0.40) | SMYD3LDHATNKSPARP2PARP1 | |
| SCHEMBL17740900 | 0.88 | SMYD3 (0.42) | SMYD3LDHATNKSPARP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086751-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086751-A1 | SWEETENER COMPOSITION | TAS2R50, TAS1R2, TAS2R10 | SMYD3 297/4885LDHA 1679/4885TNKS 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.