Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.50 |
| ▸ | NMT2 | O60551 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372369 | 0.94 | NMT2 (0.55) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL22692674 | 0.93 | NMT1 (0.52) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL21251694 | 0.92 | TLR2 (0.50) | NMT1NMT2TLR2GLP1RNOD1 | |
| SCHEMBL23626256 | 0.92 | NMT2 (0.42) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL19062765 | 0.89 | NMT1 (0.49) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL18879495 | 0.89 | TLR2 (0.52) | NMT1NMT2TLR2GLP1RNOD1 | |
| SCHEMBL23617743 | 0.89 | TLR2 (0.52) | NMT1NMT2TLR2GLP1RNOD1 | |
| SCHEMBL18973016 | 0.88 | NMT1 (0.48) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL20756558 | 0.87 | NMT1 (0.56) | NMT1NMT2TLR2GLP1RNPY1R | |
| SCHEMBL23016452 | 0.87 | NMT2 (0.49) | NMT1NMT2TLR2GLP1RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932581-B2 | Compositions and methods for modulating apolipoprotein C-III expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-03 | — | — | US | disclosed |