Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 2/20 | 0.42 |
| ▸ | NMT1 | P30419 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 3/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 6/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016499 | 0.92 | NMT1 (0.50) | NMT2NMT1ALBSIRT5TLR2 | |
| SCHEMBL20053467 | 0.90 | NMT2 (0.41) | NMT2NMT1ALBTLR2NAMPT | |
| SCHEMBL18513361 | 0.89 | NMT2 (0.40) | NMT2NMT1ALBTLR2NAMPT | |
| SCHEMBL21154983 | 0.86 | SIRT5 (0.36) | NMT2NMT1SIRT5FOLH1 | |
| SCHEMBL22372369 | 0.85 | NMT2 (0.55) | NMT2NMT1ALBSIRT5TLR2 | |
| SCHEMBL22692674 | 0.84 | NMT1 (0.52) | NMT2NMT1TLR2NOD1GLP1R | |
| SCHEMBL21251694 | 0.84 | TLR2 (0.50) | NMT2NMT1TLR2NOD1GLP1R | |
| SCHEMBL21415377 | 0.83 | TLR2 (0.43) | TLR2NOD1GLP1R | |
| SCHEMBL19239840 | 0.82 | NAMPT (0.45) | NAMPTLMNAPKM | |
| SCHEMBL19062765 | 0.81 | NMT1 (0.49) | NMT2NMT1TLR2NOD1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312964-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210207146-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2021-07-08 | — | — | US | disclosed |