SCHEMBL22692674

SCHEMBL22692674

CC(C)CCCCC(=O)NCCCCC(NC(=O)CCCCC(C)C)C(=O)NC(CCCCNC(C)C)C(=O)NC(C)C

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 6/20 0.52
▸ NMT2 O60551 5/20 0.52
▸ GLP1R P43220 8/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ NOD1 Q9Y239 1/20 0.40
▸ NPY1R P25929 2/20 0.39
▸ NPY4R P50391 2/20 0.39
▸ NPY5R Q15761 2/20 0.39
▸ NPY2R P49146 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20756558 0.95 NMT1 (0.56) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL20016499 0.93 NMT1 (0.50) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL19062765 0.92 NMT1 (0.49) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL18973016 0.91 NMT1 (0.48) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL24645937 0.90 NMT2 (0.52) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL26923325 0.88 NMT1 (0.50) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL20016485 0.88 NMT1 (0.46) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL24119975 0.88 NMT2 (0.46) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL22692615 0.87 NMT2 (0.47) NMT1NMT2GLP1RTLR2NOD1
SCHEMBL25773622 0.86 NMT1 (0.51) NMT1NMT2GLP1RTLR2NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690818-B2 Drug containing liver targeting specific ligand and thyroid hormone receptor agonist KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-07-04 — — US disclosed
US-10844379-B2 Conjugated antisense compounds and their use IONIS PHARMACEUTICALS, INC. (US) 2020-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11690818-B2 Drug containing liver targeting specific ligand and thyroid hormone receptor agonist THRA, THRB, TSHR NMT1 1981/4885NMT2 2151/4885GLP1R 16/4885
US-10844379-B2 Conjugated antisense compounds and their use CSGALNACT1, GALNT1, GALNT6 NMT1 30/4885NMT2 27/4885GLP1R 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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