SCHEMBL2001669

SCHEMBL2001669

CCCCCCCCCCCCCCCCCCNC(=O)CCc1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.65
NAAA Q02083 3/20 0.57
CASP2 P42575 1/20 0.54
MTNR1A P48039 1/20 0.52
HSD17B10 Q99714 1/20 0.51
TRPV1 Q8NER1 1/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27527714 1.00 HPGD (0.65) HPGDNAAACASP2MTNR1AHSD17B10
SCHEMBL6807560 0.87 HPGD (0.48) HPGDTRPV1
SCHEMBL6800326 0.86 TAAR1 (0.49) HPGD
SCHEMBL5404064 0.86 LMNA (0.57) HPGDTRPV1
SCHEMBL10038330 0.85 NAAA (0.60) HPGDNAAAHSD17B10TRPV1
SCHEMBL12980401 0.85 NAAA (0.60) HPGDNAAAHSD17B10TRPV1
SCHEMBL8518455 0.84 NAAA (0.58) NAAA
SCHEMBL27397541 0.84 EP300 (0.50) MTNR1AMEN1MAPTKMT2A
SCHEMBL6808007 0.83 BCHE (0.47) HPGDMAPT
Hydrochloric Acid SCHEMBL7769515 0.83 HPGD (0.62) HPGDNAAACASP2MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5954844-A BACKING SUPPORTING SURFACE-BOUND ABRASIVE PARTICLES AND ANTILOADING COMPOUND COMPRISING AN ALKYLATED OR FLUOROALKYLATED ORGANOBORON, ORGANONITROGEN, ORGANOPHOSPHORUS, ORGANOSULFUR, OR HYDROXYCARBOXYLIC ACID DERIVATIVE MINNESOTA MINING & MANUFACTURING COMPANY (US) 1999-09-21 US claimed
EP-0912295-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-05-06 EP claimed
US-5704952-A COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-06 US claimed
WO-1997042007-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-13 WO claimed
EP-1026150-B1 (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO CO LTD (JP) 2011-06-29 EP disclosed
US-6573297-B2 Applying an effective amount of (2-substituted oxyphenyl)alkanamide derivatives to the skin of a mammal for promoting hair growth SHISEIDO CO., LTD. (JP) 2003-06-03 US disclosed
US-20020052498-A1 (2-substituted oxyphenyl)alkanamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO CO., LTD. (JP) 2002-05-02 US disclosed
US-6339154-B1 THERAPY OF HAIR LOSS IN MAMMALS AND, IN PARTICULAR, IN HUMAN SHISEIDO CO, LTD. (JP) 2002-01-15 US disclosed
CN-1271724-A (2-substituted oxyphenyl) alkane acylamide derivative and hair nourishing agent, skin external use agent SHISEIDO CO LTD (JP) 2000-11-01 CN disclosed
EP-1026150-A1 (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO COMPANY LIMITED (JP) 2000-08-09 EP disclosed
US-5954844-A BACKING SUPPORTING SURFACE-BOUND ABRASIVE PARTICLES AND ANTILOADING COMPOUND COMPRISING AN ALKYLATED OR FLUOROALKYLATED ORGANOBORON, ORGANONITROGEN, ORGANOPHOSPHORUS, ORGANOSULFUR, OR HYDROXYCARBOXYLIC ACID DERIVATIVE MINNESOTA MINING & MANUFACTURING COMPANY (US) 1999-09-21 US disclosed
EP-0912295-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-05-06 EP disclosed
US-5704952-A COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-06 US disclosed
WO-1997042007-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052498-A1 (2-substituted oxyphenyl)alkanamide derivative, hair growth promoter and external composition for skin using the same NR2E1, NCOR2, DECR2 HPGD 3125/4885NAAA 1537/4885CASP2 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.