Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527714 | 0.87 | HPGD (0.65) | HPGDTRPV1 | |
| SCHEMBL5404064 | 0.87 | LMNA (0.57) | HPGDHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6800326 | 0.87 | TAAR1 (0.49) | HPGDHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2001669 | 0.87 | HPGD (0.65) | HPGDTRPV1 | |
| SCHEMBL6808007 | 0.85 | BCHE (0.47) | HPGDHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1986411 | 0.83 | ALOX15 (0.55) | HPGDL3MBTL1ACKR3LMNAGAA | |
| SCHEMBL9447533 | 0.81 | CA12 (0.57) | CA12CA2CA9TSHR | |
| SCHEMBL5415076 | 0.80 | CA1 (0.52) | CA12CA2CA9 | |
| SCHEMBL17589255 | 0.80 | HPGD (0.72) | HPGDHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6807676 | 0.79 | MEN1 (0.42) | HPGDLMNATSHRBCHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-04-08 | — | — | US | disclosed |
| WO-2000027813-A1 | AZOBENZENE DERIVATIVES AS LABELING AGENTS AND INTERMEDIATES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | CBR1, CBR3, HBB | HPGD 1634/4885HDAC1 1776/4885HDAC2 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.