Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15429134 | 0.89 | CHRNB2 (0.74) | CHRNB2CHRNA4CHRNA7ALDH1A1CCR5 | |
| SCHEMBL22767607 | 0.87 | CHRNA7 (0.73) | CHRNB2CHRNA4CHRNA7CCR5PABPC1 | |
| Water SCHEMBL26627018 | 0.85 | CHRNA7 (0.70) | CHRNB2CHRNA4CHRNA7CCR5PABPC1 | |
| SCHEMBL14951084 | 0.83 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA7CCR5 | |
| SCHEMBL12682791 | 0.82 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA7CCR5LMNA | |
| SCHEMBL20017727 | 0.81 | CHRNA7 (0.43) | CHRNB2CHRNA4CHRNA7ALDH1A1GFER | |
| SCHEMBL12014140 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CCR5PABPC1 | |
| SCHEMBL18459295 | 0.79 | LMNA (0.51) | CHRNB2CHRNA4CHRNA7ALDH1A1GFER | |
| SCHEMBL10256901 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7ALDH1A1CCR5 | |
| SCHEMBL724930 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7ALDH1A1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681247-B1 | Polymers containing an acid group and their use as a catalyst | CADENA BIO INC (US) | 2018-04-04 | — | — | EP | disclosed |