Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12624076 | 0.83 | ALDH1A1 (0.60) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL17082811 | 0.81 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL12656502 | 0.79 | L3MBTL1 (0.38) | POLBALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL12624052 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12624048 | 0.76 | POLB (0.54) | POLBMCOLN3ALDH1A1L3MBTL1LMNA | |
| SCHEMBL20739694 | 0.73 | POLB (0.49) | POLBMCOLN3ALDH1A1LMNAMEN1 | |
| SCHEMBL12622104 | 0.70 | POLB (0.55) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL12626263 | 0.68 | ALDH1A1 (0.50) | POLBALDH1A1L3MBTL1LMNANPC1 | |
| SCHEMBL12656158 | 0.66 | POLB (0.67) | POLBMCOLN3ALDH1A1LMNAMEN1 | |
| SCHEMBL10723723 | 0.65 | MCOLN3 (0.75) | POLBMCOLN3ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |