Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622139 | 0.91 | GFER (0.60) | GFERLMNAALDH1A1NPC1MAPT | |
| SCHEMBL12624024 | 0.88 | GFER (0.56) | GFERLMNAALDH1A1NPC1MAPT | |
| SCHEMBL12626996 | 0.83 | GFER (0.47) | GFERALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12623948 | 0.74 | LMNA (0.57) | LMNAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12621912 | 0.72 | GFER (0.52) | GFERLMNAALDH1A1NPC1MAPT | |
| SCHEMBL12626285 | 0.71 | ALDH1A1 (0.56) | GFERLMNAALDH1A1NPC1MAPT | |
| SCHEMBL5560091 | 0.70 | LMNA (1.00) | LMNAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL24106966 | 0.70 | GFER (0.36) | GFERALDH1A1MAPTAKR1B1POLB | |
| SCHEMBL12623932 | 0.68 | ALDH1A1 (0.56) | GFERLMNAALDH1A1NPC1MAPT | |
| SCHEMBL12626312 | 0.68 | ALDH1A1 (0.57) | GFERLMNAALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |