Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 8/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12624024 | 0.81 | GFER (0.56) | GFERHSD11B1AKR1B1POLBALDH1A1 | |
| SCHEMBL20791736 | 0.75 | L3MBTL1 (0.51) | POLBALDH1A1 | |
| SCHEMBL20019616 | 0.70 | GFER (0.54) | GFERHSD11B1AKR1B1POLBALDH1A1 | |
| SCHEMBL12622139 | 0.70 | GFER (0.60) | GFERPOLBALDH1A1MAPT | |
| SCHEMBL12626996 | 0.64 | GFER (0.47) | GFERALDH1A1MAPT | |
| SCHEMBL12622104 | 0.63 | POLB (0.55) | POLBALDH1A1 | |
| SCHEMBL15424229 | 0.63 | — | — | |
| SCHEMBL20019612 | 0.63 | POLB (0.45) | POLBALDH1A1MCOLN3MAPT | |
| SCHEMBL12624048 | 0.63 | POLB (0.54) | POLBALDH1A1MCOLN3 | |
| SCHEMBL13363622 | 0.62 | NEK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210389298-A1 | Alzheimer's Disease Assay in a Living Patient | PAIN THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | US | disclosed |