Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623903 | 0.90 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL12623892 | 0.78 | LMNA (0.46) | ALDH1A1 | |
| SCHEMBL12621853 | 0.78 | ALDH1A1 (0.48) | ALDH1A1PKM | |
| SCHEMBL17553231 | 0.77 | LIMK2 (0.39) | ALDH1A1PKM | |
| SCHEMBL12626337 | 0.75 | LSS (0.40) | ALDH1A1CYP3A4 | |
| SCHEMBL12623927 | 0.74 | CYP19A1 (0.37) | ALDH1A1 | |
| SCHEMBL23159692 | 0.73 | HSD11B1 (0.38) | — | |
| SCHEMBL12626325 | 0.72 | LIMK2 (0.44) | NAMPT | |
| SCHEMBL23159719 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL12623893 | 0.69 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |