Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12673411 | 0.87 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HCRTR1HCRTR2NPC1 | |
| SCHEMBL12624079 | 0.81 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL13353678 | 0.81 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL12673414 | 0.76 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL12662903 | 0.74 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL12621830 | 0.70 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HCRTR1HCRTR2NPC1 | |
| SCHEMBL12623948 | 0.70 | LMNA (0.57) | ALDH1A1L3MBTL1HCRTR1HCRTR2NPC1 | |
| SCHEMBL12621896 | 0.68 | HCRTR1 (0.56) | ALDH1A1L3MBTL1HCRTR1HCRTR2NPC1 | |
| SCHEMBL12624085 | 0.68 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL12626263 | 0.68 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HCRTR1HCRTR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |