Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12624085 | 0.83 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1 | |
| SCHEMBL12622062 | 0.81 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12622057 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1 | |
| SCHEMBL12626006 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15380943 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12627122 | 0.79 | L3MBTL1 (0.53) | L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL12621845 | 0.78 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1 | |
| SCHEMBL20365037 | 0.78 | HCRTR1 (0.50) | L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL12624082 | 0.77 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1 | |
| SCHEMBL12624009 | 0.77 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |