Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623977 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12624009 | 0.83 | L3MBTL1 (0.48) | HCRTR1HCRTR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL15693683 | 0.81 | HCRTR2 (0.47) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12627122 | 0.81 | L3MBTL1 (0.53) | HCRTR1HCRTR2L3MBTL1ALDH1A1HSD11B1 | |
| SCHEMBL21202626 | 0.81 | HCRTR1 (0.49) | HCRTR1HCRTR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12627108 | 0.80 | HCRTR1 (0.48) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12626027 | 0.80 | ALDH1A1 (0.49) | HCRTR1HCRTR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12623975 | 0.79 | ALDH1A1 (0.51) | HCRTR1HCRTR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12622076 | 0.78 | L3MBTL1 (0.52) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL20019664 | 0.78 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872899-B1 | ALZHEIMER'S DISEASE ASSAY IN A LIVING PATIENT | PAIN THERAPEUTICS INC (US) | 2018-07-11 | — | — | EP | disclosed |